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Search Results for " rorγt agonist 1 "

7

Compounds

Cat No. Product Name Synonyms Targets
T12751 RORγt agonist 1 Others
RORγt agonist 1 is a potent, orally bioavailable agonist of RORγt(EC50 of 20.8 nM).
T9623 RORγt inverse agonist 13 ROR
RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse agonist (IC50=63.8 nM), with improved drug-like properties[1].
T4670 SR0987 ROR
SR0987 is a RORγt agonist,
T62564 RORγt inverse agonist 30
RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist (IC50: 46 nM). Targeting the nuclear receptor RORγt is effective in the treatment of autoimmune diseases.
T79470 RORγt inverse agonist 31 ROR
RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigatin...
T72252 RORγt inverse agonist 14 ROR
RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an EC50 of 2.5 nM, exhibiting anti-inflammatory activity. It is employed in researching rheumatoid arthritis and psoriasis [1].
T36998 7β,27-dihydroxy Cholesterol 7β,27-DHC,7β,27-dihydroxy Cholesterol
7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, res...
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